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Zyprexa (olanzapine)
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5.00
Rating:

5

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Pricing
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Average Price: $395.27 Thumbs up Recommended By
53% of reviewers (of 17 reviews)
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Zyprexa®

Generic Name: Olanzapine oh-LAN-za-peen

Drug Class: Antipsychotics

 

Contents

 

Description
This medicine is classified as an antipsychotic medication and is used to treat patients that suffer from delusions, hallucinations, unorganized thought and hostility. This medicine may also be prescribed to treat severe behavioral problems in children.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Take this medicine exactly as directed by your doctor or pharmacist. This medicine should be taken continually, even if you are feeling better. Follow the directions on your prescription label. Do not take more or less of this medicine that prescribed. Do not share this medicine with other people.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Check with your doctor AS SOON AS POSSIBLE if you experience diarrhea, vomiting, unsteadiness, difficulty walking, or unusual muscle weakness.
    • This medicine can cause the following side effects:
      • contipation
      • dizziness
      • drowsiness
      • dry mouth
      • headache
      • weight gain
      • restlessness
      • mild thirst
      • frequent urination
      • drowsiness
      • fine hand tremor
      • mild nausea
    • This medicine may increase blood sugar (hyperglycemia). Diabetic patients should be cautious of this and regularly check their blood sugar.
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Warnings/Precautions
    • Several days to weeks may pass before you feel the the full effects of this medicine.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • Be cautious when driving or performing other hazardous activities. This medicine can impair judgment.
    • This medicine may reduce sweating. Be careful not to overexert yourself in hot weather.
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Overdose
Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Let your doctor know if you are taking any of the following types of medications:
      • antacids
      • antihistamines
      • diet pills
      • benztropine (Cogentin)
      • bromocriptine (Parlodel)
      • carbamazepine (Tegretol)
      • dicyclomine (Bentyl)
      • fluoxetine (Prozac)
      • guanethidine (Ismelin)
      • lithium
      • meperidine (Demerol)
      • methyldopa (Aldomet)
      • phenytoin (Dilantin)
      • propranolol (Inderal)
      • sedatives
      • trihexyphenidyl (Artane)
      • valproic acid (Depakene)
      • cold medications
      • medications for depression
      • vitamins and herbs
    • Inform your doctor of all the medications you may use (both prescription and nonprescription), especially if you are taking any of the following:
      • anti-depressant
      • anti-anxiety drugs
      • sparfloxacin
      • grepafloxacin

      • guanethidine
      • guanadrel
      • lithium
      • metrizamide
      • cabergoline

      • tranquilizers
      • barbiturates
      • sleeping pills
      • narcotic pain
        medication (e.g. codeine)
      • other medicines that make you drowsy.
    • Many cough-and-cold products contain ingredients that may add a drowsiness effect. Before you use cough-and-cold medications, ask your doctor or pharmacist about the safe use of those products..

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Pregnancy/Nursing
Tell your doctor if you are pregnant or planning to become pregnant. For women: since this medicine is excreted in human breast milk, you should NOT breastfeed while taking this medicine.
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More Information

There may be slightly increased risk of serious, possibly fatal side effects when this medicine is used in elderly patients with dementia. Talk to your doctor for more information.
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Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.




Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.













 


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razeljenny
Veteran Member

Registered: May 2006
Location: Wasington State
Posts: 353
Review Date: Thu July 6, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 9 

 
Positive aspects of the product (pros): cleared my head, immediately calming
Negative aspects of the product (cons): might be lead tired at any given time on this med if not careful about dosing yourself

This drug is very good, yet the side effect of tiredness, comes with no warning. It does clear your mind when fustrated. I am bi-polor and it helped me to quit being manic, which was comforting and good. I did gain too much weight from it. It really cleared my mind and I had crisp feeling and self-control, (less impulsive-which I tend to be, when untreated) So besides the weight gain and the tiredness with no warning the drug is effective for my mania. I am now using Morinda Citrafola (works for me but doesn't necessiraly mean it will help others in the same fashion- See alternative treatment section of supportgroup) It helped when I was under stress going crazy with my mate, because I was getting parinoid. I had to cut the 10 mg pills into quarters and use it 4 times a day rather than take it all at once. It was very helpful with my mental health but I think the smalled increments had something to do with it, controlling, thus trying to prevent lead tired spells which I noticed as it's worst side effect. The weight gain was less important, whereas the drug was so good in treating my mental health problem that the benefit far outweighed the harm with this drug. I took this drug in this fashion for 6 or 7 years and it helped me a great deal to have a better life. I recommend it to people that want to move beyound their past and to grow. I think the dosing could be the only question about it.
monique68
Visitor

Registered: September 2006
Posts: 1
Review Date: Tue September 5, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 2 

 
Positive aspects of the product (pros): helped with auditory hullicinations
Negative aspects of the product (cons): gained over 50 lbs. increases appetite for carbs

This drug caused all my weight problems which is just as depressing as the mood.
Anamitra
Visitor

Registered: September 2006
Posts: 3
Review Date: Thu September 21, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Positive aspects of the product (pros): able to think clearly, no hallucinations or delusions
Negative aspects of the product (cons): weight gain, sometimes don't have a period

Zyprexa made me have a much more normal life than without medication. I was having delusions and spinning in circles, walking in circles, thought I was an angel, and wouldn't eat. This medicine gave me a new life. The only thing is my doctor once lowered the dosage I was taking and I became suicidal, so I had to go back to 5 mg and I feel fine with no voices or hallucinations or anything. Just clear thinking.
CaraD
Junior Member

Registered: September 2006
Posts: 8
Review Date: Thu September 28, 2006 Would you recommend the product? Yes | Total Spent: $12.80| Rating: 8 

 
Positive aspects of the product (pros): keeps me focused, allows me to start something and finish it, curbs some intrusive thoughts
Negative aspects of the product (cons): high blood sugars b/c of it

It is very expensive so you will need ins. or a free prescription drug plan. Lilly does offer it for free to qualified people. I think it works very well.
Sarah116

Grand Poohbah

Registered: August 2006
Posts: 1623
Review Date: Sun December 24, 2006 Would you recommend the product? Yes | Total Spent: $998.00| Rating: 7 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): Weight gain, hunger drive +!

Side effects,It was gentle except the hunger drive which causes a lot of weight gain Sad! It does not zonk you out like some medications. Symptoms I am not so sure about.
manic1
Visitor

Registered: February 2007
Location: Kansas City Area
Posts: 2
Review Date: Wed February 28, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 5 

 
Positive aspects of the product (pros): helped me to think mor clearly once my body adjusted to the dosage
Negative aspects of the product (cons): I gained 80 pounds in one year

The weight gain is enough to make anyone depressed. It is also VERY difficult weight to take off. The psychiatric aspects of this med were good enough to stay on it long enough until something better came out on the market for me, and that was Abilify.
bdog1

Visitor

Registered: March 2007
Location: alabama
Posts: 1
Review Date: Mon March 26, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Positive aspects of the product (pros): helps clear my mind and lets me function better in life. Saved my marriage
Negative aspects of the product (cons): heard alot about weight gain. only been on it 6 weeks no significant weight changed thank god.

helps clear my mind and lets me function better in life. Saved my marriage
jattitude74
Member

Registered: March 2007
Posts: 128
Review Date: Wed April 4, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): gained 25 pounds in 3mo.!!!!!

I was on it for 3 mo. and gained a lot of weight it also had no effect on me even though my dr.kept upping my dose. Glad it works for some but I had no luck
tabi1818

New Member

Registered: September 2007
Location: canada
Posts: 3
Review Date: Fri September 28, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): made me dizzy, nauseous and panicky

I took one 5mg pill and slept for 18 hours straight. When I finally woke up was so groggy, dizzy and felt terrible for the next 2 days. My doctor told me not to take anymore pills.
ImGoingSane
Junior Member

Registered: October 2007
Location: Fort Wayne IN USA
Posts: 5
Review Date: Mon October 8, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 5 

 
Positive aspects of the product (pros): No intense emotions at all
Negative aspects of the product (cons): No intense emotions at all, Weight gain!!, intense sedation

I was on this and I missed weeks of school because I had no impulse of wanting to wake up. Before I would go to bed I would eat like one of those little Japanese guys in the eating competitions. Didn't really care for acting like a zombie and pretty much forgetting a good year of my life due to apathy and being tired. This medication might be good for someone institutionalized or some one who doesn't really interact with anyone in the first place but definitely not for people who want to have fun and be able to wake up every morning and not every afternoon. Took forever to find the right dosage. Zyprexa also killed my sex drive. Read Crazy by Pete Earely and it hits the nail on the head on how it made me feel. I hear this medication also causes diabetes and makes your ticks worse after you get off of it too.
anna342
Member

Registered: March 2007
Location: England
Posts: 96
Review Date: Mon November 5, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Positive aspects of the product (pros): Helped with sleep
Negative aspects of the product (cons): Made me eat way too much

I only stayed on it a week because I couldn't stand how much it made me eat. It did help with sleep though.
Review Date: Thu November 8, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): .. I guess I was calm
Negative aspects of the product (cons): Massive drowsy side effect

For mania I was on it for one day and I could not get off of the bed! My doctor immediately pulled me off of this medication because it made me drunk and completely out of it...
CMac73
Visitor

Registered: December 2007
Posts: 4
Review Date: Thu December 6, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 5 

 
Positive aspects of the product (pros): Calming and relaxing drug
Negative aspects of the product (cons): Weight gain, stomach upset

I have taken Olanzapine on and off for about 4 years for Bipolar Mixture Affective. I was given it instead of Risperidone. My weight went from 7 1/2 stone to about 10 stone. I felt very good mentally and nothing really bothered me. I have tried many similiar drugs, Olanzapine was a favourite but I am concerned about side effects of the drug, such as diabetis, I know somebody who got it after taking it. It also interferes with your hormones and I get a massive stomach on it, which is horrible, exercise doesn't do a thing for it, I think it must be water retention! Also I think it is starting to wreck my stomach causing wind and constant hunger pangs also sleeping until 2.00pm. I switched to Seroquel for it didn't work the same mentally. I am trying Abilify again at a low dose because I think it is the closest I can get to feeling good mentally but without the concerns.
weirdkitty

Visitor

Registered: January 2008
Location: USA
Posts: 1
Review Date: Tue January 1, 2008 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): none
Negative aspects of the product (cons): zombie, zero personality, excessive drowsiness.

I was prescribed 2.5 mg Zyprexa back in February 2003 in addition to 100 mg Topamax and 75 mg Effexor XR for Bipolar II. The shrink told me it worked great for anxiety and it would augment the Effexor XR.


I took it for approximately three months. It knocked me out for 10-12 hours each night; and if time allowed I would take a nap in the afternoon. That really sucks when it's a daily occurance! When I was awake (which was often less than half the dang day), I felt like a zombie! It was horrid! My thinking was slowed, I rarely experienced strong emotion, I had next to no creativity, and I was even quieter than normal.


I ended up taking myself off. I didn't want it to dictate my life anymore! Three months was more than enough time to give it a chance, but not so long that a huge chunk of time was "lost".
teejai
Grand Member

Registered: May 2007
Location: England
Posts: 641
Review Date: Thu January 17, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Positive aspects of the product (pros): Made me feel calmer, more at peace within myself,less of a 'war zone' in my head
Negative aspects of the product (cons): Made me feel very tired

I found this was therapeutically most effective for me in terms of symptom relief at 10mgs but had major problems at that dose with feeling 'zombified' which
meant due to other issues at the time (looking after wife with vasc dementia)i had stop taking it. Now on 2.5 mgs which doesn't work as well but no 'zombie effect'.
Would have preferred to have been slowly titrated to up to 10mgs or alternatively slowly titrated down to a dose that combined max therapeutic effect with min side effect.
MyBestKids2
Elder

Registered: September 2006
Posts: 5349
Review Date: Sun May 11, 2008 Would you recommend the product? Yes | Total Spent: $175.00| Rating: 10 

 
Positive aspects of the product (pros): eliminated voice, decreased racing thoughts
Negative aspects of the product (cons): minimal weight gain

The price for a 30 day supply of 10 mg is $458. Helping me obtain some sanity is priceless
LLMF
Visitor

Registered: July 2008
Location: Wisconsin
Posts: 9
Review Date: Tue July 8, 2008 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 5 

 
Positive aspects of the product (pros): Knocks you out
Negative aspects of the product (cons): Incapacitated in the morning

I was given this in the hospital to help me get to sleep. I guess if you want to sleep or drug someone this is the stuff. Personally I never want to wake up not being able to keep my eyes still or not being able to form complete sentences again. I think the doc was actually a little shocked from how eff'd up I was. lol at least they didn't give me anymore meds after that


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