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Paxil (paroxetine)
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4.02
Rating:

4.02
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45% of reviewers (of 42 reviews)
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Paxil®

Generic Name: Paroxetine pa-ROX-e-teen

Drug Class: Antidepressant, SSRI

 

Contents

 

Description
This medicine is used to treat depression or anxiety. Your doctor may prescribe this medicine for other conditions as well.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
This medicine should be taken about the same time every day, morning or evening and can be taken with or without food. This medicine may take up to 4 weeks to reach full effect, but you may see symptoms of depression improving in as little as 1-2 weeks.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • dry mouth
    • tremor or muscle spasms
    • nervousness
    • trouble sleeping
    • headache, drowsiness
    • nausea
    • drowsiness
    • insomnia
    • headache
    • increased sweating
    • dizziness, lightheadedness
    • changes in sexual function
    • Unreported side effects are possible, talk to your healthcare provider if any other symptoms occur.
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Warnings/Precautions
    • This medicine may cause drowsiness or dizziness.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • Smoking cigarettes can decrease the effectiveness of this medicine.
    • If you are planning to have surgery, let your doctor know.
    • Do NOT take this medicine if you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] in the last two weeks.
    • This medicine can increase the risk of suicidal thinking and behavior in some children and teens. Parents of children taking antidepressants should watch for signs of worsening depression or unusual changes in behavior.
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Overdose
Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • If you are taking a tricyclic antidepressant, talk to your doctor before taking this medicine.
    • St. John’s Wort should be avoided while taking this medicine due to the additive effects of serotonin.
    • Tell your doctor if you are taking any of the following drugs:
      • blood thinners (Coumadin)
      • other antidepressants
      • metoprolol
      • antihistamines
      • carbamazepine (Tegretol)
      • cimetidine (Tagamet)
      • estrogens
      • fluoxetine (Prozac)
      • intraconazole (Sporanox)
      • ketoconazole (Nizoral)
      • levodopa
      • lithium
      • muscle relaxants
      • birth control pills
      • sleeping pills
      • thyroid medications
    • Do not take this medicine with thioridizine, or within 5 weeks of taking this medicine.
    • Caution should be exercised when taking this medicine certain antibiotics, such as erythromycin, clarithromycin, or azithromycin.
    • If you are taking medications for migraines such as Imitrex, talk to your doctor before starting this medicine.
    • This medicine should not be taken with MAO inhibitors. If you think you are taking an MAO inhibitor talk to your doctor or pharmacist.

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Pregnancy/Nursing
If you plan on becoming pregnant, discuss the benefits versus the risks of using this medicine while pregnant. Because this medicine is excreted in the breast milk, nursing mothers should not breastfeed while taking this medicine.
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More Information

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other benefits. However, studies have shown that a small number of people (especially children/teenages) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with a doctor about the risks and benefits of antidepressant medication, even if the treatment is not for a mental condition. Tell your doctor immediatley if you notice worsening depression, unusual behavior changes, (including possible suicidal thoughts/attempts), or other mental/mood changes. Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.
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Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.



Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.

 

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Author
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razeljenny
Veteran Member

Registered: May 2006
Location: Wasington State
Posts: 353
Review Date: Thu July 6, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 10 

 
Positive aspects of the product (pros): Definately took away dysphoric moods
Negative aspects of the product (cons): sometimes I get hyper, can't always sleep, overstimulated

All and all this has been so good for me. I have social anexity and it takes it away and I get relaxed and stay that way most of the time. I have joyousness and feel light and carefree, which I need to be because I don't enjoy being STUCK in depression (which can go on for weeks, me staying in my room for days at a time) I have been living an almost normal life and make friends when I stay on my Paxil.
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bigdog1263
Member

Registered: September 2006
Location: Pennsylvania
Posts: 28
Review Date: Mon September 11, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Positive aspects of the product (pros): average effectiveness for anxiety.....no dependency potential
Negative aspects of the product (cons): side effects

"paxil Porkers" I put on 23lbs in one month....after having lost 98lbs!!!!!!
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myself
Grand Magnate

Registered: July 2005
Posts: 3291
Review Date: Tue September 12, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons):

I had little to no side efects with this medication. the only problems I had were in general I had to move slowly because if I sat up to fast I got dizzy. When I first started on it, it made me tired so my doctor switched me to taking it at night instead of during the day, that way I could sleep through the side effects of it stabilizing the medication level in my body every night but have the benefits of the leveled out medication during the day. this worked out very well for me.


If I missed a dose or did not take it at the same time every night I experienced an electric shock type pain in my head. once I got into the habit of setting an alarm and taking it on time the shock feeling went away.


I had the electric shock feeling when coming off the medication too dispite I was on the lowest dose possible.


This medication is definately one that needs to have a doctors help in stopping the medication so that the person can be weaned off it little by little. it took me 2 months to come off it at the 10mg level and not experience the electric shock in my head feeling.


One plus to this medication - when I was at the 10 mg level and I needed a higher dosage after being on it for a year but I was unable to handle a higher dosage another medication - welbutrin CR - was added with absolutely no adverse reaction.


I am leaving the recommendation turned on to yes because one persons medication flop can also be another persons miracle drug.
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eskielover
Magnate

Registered: October 2004
Location: Harrodsburg, Kentucky, USA
Posts: 2587
Review Date: Thu September 14, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 2 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): caused uncontrollable shaking, naysea, dizziness, & migraine pain

Paxil is the brand name for paroxetine. I was only on paxil for a very short try it period of time. Immediately after taking is, I went into uncontrollable shaking. Added to that came nausea, dizziness & horrible migraine pain. These effects were bad enough that I couldn't tolerate them long enough to see if they would go away with time or not.
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Rainbowzz
Grand Magnate

Registered: December 2005
Location: Nova Scotia, Canada
Posts: 4657
Review Date: Thu September 14, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): nil - perhaps a slight lessening of anxiety
Negative aspects of the product (cons): made me become borderline psychotic, nauseaus, caused suicidal ideattion

Had a horrible time with this one. Made me shakey and nauseaus, suicidal, what i term borderline psychotic (anxious, hearing things, seeing things out of the corner of my eye, delusions ect)


I would not reccomend this one at all.
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Perzephone
Veteran Member

Registered: May 2005
Location: Las Vegas, NV
Posts: 432
Review Date: Tue September 19, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): None
Negative aspects of the product (cons): Sensory overload, dizziness, nausea

I took Paxil for less than a week - it made me incredibly sensitive to stimulus - normal low household lighting was incredibly bright, the volume of the television or people talking in normal tones was overwhelming, even my skin felt funny against my clothing or upholstery. I was dizzy, nauseous and wanted to hide in a dark hole with nothing touching me. After about 3 days, I began to have a peculiar 'empty-headed' feeling - like I could be watching a dimmed television without 'thinking' about what I was seeing. I work in a casino, and the sensory overload was just too much so I discontinued the drug.
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Enigmatik
Member

Registered: October 2006
Location: Canada
Posts: 63
Review Date: Sun October 8, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): None
Negative aspects of the product (cons): I only took one dose 20mg of Paxil, I had head zaps, numbness, nausea, dizzy, felt disconnected, confused, terrified.

I took one pill @ 20mg dosage and I though I was going to die, I was sick for 4 days after it, vomiting, dizzy, sweating, shaking, confused, staring into space, swirly vision, electric zapping in my head, my legs and arms/hands would fall asleep at random (the painful kind) my speech was off, 4 day migrain with tunnel vision and pain! it was a big bad horrible rollercoaster apparently due to hypersensitivity to the drug, my brain literally went haywire, i would NEVER recommend this drug, its evil! To top it off the panic only became more severe Sad
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AlteredState01
Poohbah

Registered: October 2006
Location: Canada
Posts: 1059
Review Date: Tue October 10, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): Zero
Negative aspects of the product (cons): Gave me anxiety attacks!

Took for depression. I never experienced an anxiety attack UNTIL I started taking this medication.


Did not help me at all. As a matter of fact, I continue to experience high anxiety ever since taking this med. I have noticed, though, that since I began having anxiety attacks, I no longer get migraines. Weird, eh?


Friends that have been on this med have had positive experiences and worked well for them. It just wasn't for me.
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Rebound
Veteran Member

Registered: December 2004
Location: Nova Scotia, Canada
Posts: 355
Review Date: Mon November 6, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): side effects

My experience with Paxil was awful. I had terrible diarrhea contstantly for as long as I was taking it. I realize I may be unique in that but still, I had to stop taking it within a week.
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Amerikasend
Member

Registered: December 2006
Location: Merryland
Posts: 28
Review Date: Mon December 4, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): everything about it

This stuff is garbage. I can't believe pdoc's even prescribe this crap to people. I have been on a few med's in my history and this one was the worst, wellbutrin being the second worst. I ended up be nausous, light headed/dizzy, hallucinations, had real bad diarrhea (I was a human espresso machine, brewing up non-stop butt coffee), bad headaches, and just felt hopeless.
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URIIADDIVME
Member

Registered: September 2006
Posts: 40
Review Date: Mon December 18, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): caused severe tremors

Caused tremors so severe I could not control movement, could not sleep, could hardly function.
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purplesunny
New Member

Registered: September 2006
Location: California - Central Valley
Posts: 25
Review Date: Tue December 19, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 10 

 
Positive aspects of the product (pros): I loved paxil. It made me not get upset at day to day things
Negative aspects of the product (cons): my psychiatrist took me off when he "discovered" I was hypo-manic. He then put me on Depakote, Buspar, Remeron, Melleril and something else I can't remember

I had medical insurance at the time I took it, so I only had to pay a small co-pay, like $20.


The only negative side effect I had was sexual.
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etherealpunk
Visitor

Registered: December 2006
Location: Tallahassee, Fl
Posts: 2
Review Date: Thu December 21, 2006 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 5 

 
Positive aspects of the product (pros): Helps control the "downs"
Negative aspects of the product (cons): Brings on more "ups", headaches

Works really well for keeping panic at bay, but tends to enourage more manic episodes in those like me, with bipolar problems. It is probably the best treatment I've had though, since I am being treating for more than one disorder...it helps keep me on an even keel. Headaches are a problem when getting used to it.
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Joepesto
Member

Registered: November 2004
Location: Northern California
Posts: 72
Review Date: Wed December 27, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 2 

 
Positive aspects of the product (pros): It did help with depression
Negative aspects of the product (cons): Headaches, clouded thinking, difficult to quit.

This is an awful medication. I would not recommend it. I am still suffering the residual side effects from trying to stop taking the drug. The rebound effect when quitting caused me to become very suicidal.
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Review Date: Thu December 28, 2006 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): NONE
Negative aspects of the product (cons): Did not work for me

After taking Paxil for 7 days my depression got so bad I was suicidal. 7 days off of it and I was back to feeling "blah".
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mama2ak
Visitor

Registered: December 2006
Location: Minnesota
Posts: 14
Review Date: Sat December 30, 2006 Would you recommend the product? Yes | Total Spent: $20.00| Rating: 10 

 
Positive aspects of the product (pros): Effective, generic!
Negative aspects of the product (cons): amnesia, feeling dependent, withdrawal difficulties, low libido

I was on this for about 8 years straight and I'm practically amnesic to the little details of those years. I started to feel dependent on it after awhile and when I withdrew off of it, felt like I was in a bubble, losing my mind. It also killed my libido.


On the plus side, i was agoraphobic and homebound and this drug gave me the ability to leave my house again. It also completely ceased my irritable bowel symptoms. For those reasons alone, I would still recommend it to people, even tho the side effects are rampant.
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graydove
Junior Member

Registered: January 2007
Location: Oregon
Posts: 5
Review Date: Fri January 5, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 4 

 
Positive aspects of the product (pros): Great for Depression, and obsessive thoughts
Negative aspects of the product (cons): Muscle spasms

I liked this medication for as long as I could take it. Eventually I had to stop or never be able to lay down and rest. Everytime I almost entered into a deep sleep I had restless legs and then the rest of my body would start into muscle spasms. It was the best me I have ever had for my depression, but it was not the right one for me. I will rate this at a 5 in the aspect it was the best antidepressent I had been on, but i would have to say a 0 in regards for me ever taking it again. Eventually The Muscle Spasam begain in daytime. Blessings Graydove
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ExSleeper
New Member

Registered: February 2007
Location: Michigan
Posts: 3
Review Date: Mon February 19, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Positive aspects of the product (pros): Able to face the world and take better care of my children
Negative aspects of the product (cons): Weight gain, IBS,insomnia

I was originally diagnosed w/ post-partum depression 5 yrs ago and was put on Paxil. Have since been diagnosed with chronic depression, insomnia, and social phobia. A few different docs have tried to change me along the way, and had me try: Wellbutrin (hated it), Effexor (hated it), Prozac (made me mad), Zoloft (didn't work), Trazadone (he** no!), Xanax (loved it a little too much), and just today put me on 20 mg Elavil along w/ my current 40 mg Paxil. Paxil has always been my fall-back drug; I'm relaxed, patient, somber, social and less emotional when I take it. I'm willing to accept the side effects in exchange for the way I'm able to handle life and am just able to live.
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Juliana
Grand Member

Registered: March 2007
Location: Canada
Posts: 933
Review Date: Sat March 3, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): none
Negative aspects of the product (cons): severe diarrhea, nausea, shaking, confusion, dehydration

I had a horrible reaction to Paxil. I took one 20mg tablet and within a few hours I started feeling extremely nauseous and shaky. I went to bed and woke up a few hours later feeling much worse. I was nauseous and had severe diarrhea (just bile) for the next 10 hours. I was shaking and confused. I passed out at one point and didn't have the strength to pull myself up off the floor. My vision was blurred and my head was spinning and I couldn't control my shaking. I remember feeling like I was dying and wanted to call 911 but didn't have the strength to reach the phone. I ended up in hospital for dehydration and was in bed feeling nauseous and shaky for 6 days afterwards. Paxil scared me. It was more than a year before I was willing to try another drug for my anxiety. I eventually started taking Celexa and that worked well for me with minimal side effects.
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lunakit
Visitor

Registered: April 2007
Posts: 12
Review Date: Thu April 12, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 3 

 
Positive aspects of the product (pros): eliiminated panic attacks, easier to socialize
Negative aspects of the product (cons): mania, agitation, aggressiveness, outbursts of temper, sleeplessness, strange electrical shocks during withdrawal

I'm bipolar with a tendency toward dysphoric mania. I also have GAD, social phobia and get PAs. I took this along with 4mg/day of xanax for a few months several years ago during my pdoc's SSRI phase (we also tried Wellbutrin, which didn't work for me in the long run either). I liked Paxil at first. I felt more comfortable around people and didn't get PAs. But after a few months (I lasted longer on this than on Wellbutrin) I started becoming more and more angry-manic, pissed off all the time and picking fights with everyone. And sleep? Forget it. Also, for about 3 weeks after stopping Paxil I would occasionally get odd "electrical shock" feelings. Beware of SSRIs if your bipolar disorder scews towards mania. It might work well for depressives or social phobics who aren't also manic but my pdoc gets a 1 for prescribing this for a mostly-manic patient!
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savinmyself
Visitor

Registered: April 2007
Location: Virginia
Posts: 4
Review Date: Fri April 20, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros):
Negative aspects of the product (cons): so many!!!!

I took paxil and had to take ambien while i was on it, i'm bi-polar so it made my mania's so bad i couldn't even deal with it, then when i tried to come off it it hurt my head REALLY REALLY bad, took a week to wean off! The docs tried to give it to me again when i went into the hospital, they wouldn't let me go home till i did cuz so i took the 1 pill there and when my husband got me home i refused to let him fill the perscription. I suggest lexapro.
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terry
Junior Member

Registered: April 2007
Posts: 8
Review Date: Tue April 24, 2007 Would you recommend the product? Yes | Total Spent: $1.00| Rating: 10 

 
Positive aspects of the product (pros): great antidrepressant, keeps anxiety down, very little side effects
Negative aspects of the product (cons): weight gain, mainly

I see this antidepressant has a low rating, but to me it is one of the best there is. Since all SSRIs cause weight gain, that's just the price of not being depressed.
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jimmyjetta
Visitor

Registered: May 2007
Posts: 8
Review Date: Sun May 13, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 6 

 
Positive aspects of the product (pros): it works
Negative aspects of the product (cons): sexual side effects

Antidepressant properties are solid. It works well.


I generally only get one side effect from antidepressants: no matter which one it is, if it demonstrates even the smallest possibility of causing sexual side effects then I'm going to be the person who has problems with it.


Catch 22.
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buzzie
Visitor

Registered: March 2006
Location: Southern CA
Posts: 7
Review Date: Thu August 2, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 3 

 
Positive aspects of the product (pros): Helped my mood big time
Negative aspects of the product (cons): weight gain/ hard to get off

I would have to recommend this because it did work "for me". The only thing is that I gained way too much weight. I tried going off this med and it was hell. So beware of getting off this med. I could hardley get out of bed weaning myself off this med. I'll never take it again.
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xd42
Junior Member

Registered: August 2007
Posts: 5
Review Date: Sat August 25, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 8 

 
Positive aspects of the product (pros): Reduces both anxiety and depression
Negative aspects of the product (cons): constipation, weight gain, sweating increase, decreased libido

Paxil has some side effects but I've found it effective for helping me manage both anxiety and depression. I've come to accept the fact that no pill is going to completely "fix" my anxiety and depression but at least with Paxil I can manage. And manage is good enough. I recently tried life without meds and found the anxiety and depression was too much to tolerate. I tried Wellbutrin at the urging of my doctor but it didn't work for me. Now I'm back on Paxil and life is beginning to be enjoyable again. When I was off Paxil, the depression/anxiety and my desperation for relief was getting really scary. Thankfully, things are returning to normal again after a few weeks back on Paxil. The relief is well worth the price of the side effects.
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xp1155
Member

Registered: August 2007
Location: Ohio
Posts: 42
Review Date: Sun August 26, 2007 Would you recommend the product? Yes | Total Spent: None indicated| Rating: 7 

 
Positive aspects of the product (pros): slight reduction in anxiety
Negative aspects of the product (cons): dry mouth, no relief from depression (for me)

This did not help my depression, but it did help slightly with my anxiety. I did not continue the treatment because my anxiety id not daily and I mainly wanted it for depression. Side effects were minimal for me. If you suffer from anxiety daily and depression, this might be a good place for you to start.
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willezurmacht
Visitor

Registered: September 2007
Posts: 1
Review Date: Mon October 1, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 1 

 
Positive aspects of the product (pros): none
Negative aspects of the product (cons): horrible

I took Paxil in 1994 and it essentially ruined my life at the time. Zoloft was like a Godsend after it. I have only now begun to rebuild my life after the damage done by Paxil. It ruined my relationships and I even was forced to drop out of school.
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Sultrysorrow
Member

Registered: October 2007
Location: North Carolina
Posts: 50
Review Date: Wed October 3, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Positive aspects of the product (pros): Works well for a while if things stay the same.
Negative aspects of the product (cons): Does not work well if things are falling apart.

Out of all meds I was hoping that this one would help
when the walls around me came crashing down.
Instead I ended up in the crazy house.
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cjta
Visitor

Registered: October 2007
Posts: 1
Review Date: Fri October 12, 2007 Would you recommend the product? No | Total Spent: $0.50| Rating: 2 

 
Positive aspects of the product (pros): no highs/no lows
Negative aspects of the product (cons): no highs/no lows

Paxil withdrawal symptoms are excrutiating and debilitating.
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pyewacket
Member

Registered: October 2007
Location: ontario, canada
Posts: 22
Review Date: Mon October 22, 2007 Would you recommend the product? No | Total Spent: None indicated| Rating: 4 

 
Positive aspects of the product (pros): unsure
Negative aspects of the product (cons): unsure

not sure is this helped me or not.
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102riley
Visitor

Registered: October 2007
Location: Southeast Alabama
Posts: 9
Review Date: Mon October 22, 2007 Would you recommend the product? Yes | Total Spent: $22.00| Rating: 8 

 
Positive aspects of the product (pros): I actually have used Paxil CR for a long while now. It has deffinently boosted my mood
Negative aspects of the product (cons): I really haven't had any bad side effects. I would like it , if it boosted my mood more

I f