Generic Name: Thiothixene (thy-oh-THIX-een)

Drug Class: Antipsychotic


Drug Uses

Thiothixene is classified as an antipsychotic medication and is used to treat schizophrenic patients that suffer from delusions, hallucinations, unorganized thought and hostility. Thiothixene may be prescribed by your doctor for other uses as well.

General Information

This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.

How it Works

It works by helping to restore the balance of certain natural chemicals in the brain. These chemicals are referred to as "neurotransmitters".

How to Take It

Take this medicine exactly as directed by your doctor or pharmacist. This medicine should be taken continually, even if you are feeling better. Thiothixene comes as a capsule and a liquid concentrate to be taken by orally. This medicine is generally given two to three a day. Follow the directions on your prescription label. Do not take more or less of this medicine that prescribed. Do not share this medicine with other people.

Possible Side Effects

    • Thiothixene can cause side effects. If these side effects are severe or don't go away:
      • contipation
      • dizziness
      • drowsiness
      • dry mouth
      • headache
      • weight gain
      • restlessness

    • Contact your healthcare provider right away if you experience and of the following:
      • confusion
      • difficulty breathing
      • eye pain or discoloration
      • fever
      • fast or irregular heartbeat
      • shuffling walk
      • slow or jerky movements
      • seizures
      • rash
      • severe muscle stiffness
      • problems urinating
      • unusual movements of the face or jaw
      • unusual tiredness
      • unusual bleeding or bruising
      • yellowing of the skin or eyes


    • Let your doctor know if you are allergic to thiothixene or any other medications.

    • Tell your doctor if you have or have had any of the following:
      • allergies
      • angina (chest pain)
      • asthma
      • blood disorders
      • high blood pressure
      • chronic bronchitis
      • depression
      • emphysema
      • glaucoma
      • history of alcohol abuse
      • irregular heartbeat
      • liver or kidney disease
      • urinary or prostate problems

    • Tell your doctor or dentist that you are taking this medicine if you are having surgery.

    • This medicine can cause dizziness or drowsiness.

    • Alcoholic beverages can increase the effects of this medicine and should be avoided.

    • Avoid long exposure to the sun and use a sunscreen and protective clothing. Thiothixene make increase your skins sensitivity to sunlight, making it easier for you to burn. This includes sunlamps.


    • Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

Drug Interactions

    • Tell your doctor about all of the medications you take including those over-the-counter.

    • Let your doctor know if you are taking any of the following types of medications:
      • antacids
      • antihistamines
      • diet pills
      • benztropine (Cogentin)
      • bromocriptine (Parlodel)
      • carbamazepine (Tegretol)
      • dicyclomine (Bentyl)
      • fluoxetine (Prozac)
      • guanethidine (Ismelin)
      • lithium
      • meperidine (Demerol)
      • methyldopa (Aldomet)
      • phenytoin (Dilantin)
      • propranolol (Inderal)
      • sedatives
      • trihexyphenidyl (Artane)
      • valproic acid (Depakene)
      • cold medications
      • medications for depression
      • vitamins and herbs

Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.


Tell your doctor if you are pregnant or planning to become pregnant. For women: since thiothixene is excreted in human breast milk, you should NOT breastfeed while taking this medicine.

More Information

For more information, talk to your doctor, pharmacist or health care provider.

Last reviewed: By John M. Grohol, Psy.D. on 19 May 2015
    Published on All rights reserved.