Generic Name: Duloxetine hydrochlorideDrug Class: Antidepressant, SSNRI
- Drug Uses
- General Information
- Proper Use of this Medication
- Possible Side Effects
- Warnings and Precautions
- Drug Interactions
- Missing a Dose
- Pregnancy or Nursing
This medicine is a selective serotonin and norepinephrine reuptake inhibitor
(SSNRI). Cymbalta is used to treat depression. This medicine is also used
for nerve pain (peripheral neuropathy) in diabetic patients. Your doctor may
prescribe this medicine to treat other conditions.
This information is for educational purposes only. Not every known side effect,
adverse effect, or drug interaction is in this database. If you have questions
about your medicines, talk to your health care provider.
Proper Use of this Medication
Follow the directions printed on your prescription label. Ask you doctor
or pharmacist if you have any questions about how to take this medicine. Cymbalta
should be taken by mouth. This medicine should be swallowed whole and should
not be chewed or crushed, nor should the contents be sprinkled on food or
mixed with liquids. All of these might affect the enteric coating. Do not
quickly stop this medicine without talking to your doctor.
Possible Side Effects
- Talk to your doctor if these side effects are bothersome or do not go
- increased sweating
- sexual problems
- A few of the most common side effects with this medicine include:
- dry mouth
- increased sweating
- If you experience other bothersome side effects, contact your health
- Patients and their families should be alert to personality changes such as increased agitation or talk of suicide.
- Do NOT stop taking this medicine without first talking to your doctor.
- Alcoholic beverages can increase the effects of this medicine and should be avoided.
- This medicine may cause drowsiness or dizziness.
- Before taking this medicine, notify your doctor if you have:
- history of alcohol abuse
- narrow-angled glaucoma
- kidney problems
- Patient should watch for worsening depression or suicidal tendencies.
If you are feeling more agitated, talk to your health care professional.
- Be cautious when driving or performing other hazardous activities.
- Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.
- Patients should be advised to inform their physicians if they are taking, or plan to take, any prescription or over-the-counter medications, since there is a potential for interactions.
- If you are taking a group of medicine called "MAO inhibitors", they cannont be taken with this medicine. Stop the MAO inhibitor 14 days prior to starting this medicine. Your doctor or pharmacist can assist you with this.
- Before taking any new medications, either prescription or over-the-counter (OTC), talk to your doctor or pharmacist about mixing medicines.
- Avoid taking St. John's Wort with this medicine.
Keep this medication in the container it came in, tightly closed, and out
of reach of children. Store it at room temperature and away from excess heat
and moisture. Throw away any medication that is outdated or no longer needed.
Patients should be advised to notify their physician if they become pregnant
or intend to become pregnant during therapy. Neonates exposed to SSRIs or
SNRIs late in the third trimester have developed complications requiring prolonged
hospitalization. (1) Nursing is not recommended while taking this medicine.
More InformationFor more information about this medicine, talk to your healthcare provider.
Last reviewed: By John M. Grohol, Psy.D. on 19 May 2015
Published on PsychCentral.com. All rights reserved.